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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b31ab2f21b29c4b794617bb733cba7eb67eb67d73cb91dc0d4e7373c8fa466f1' 
  AND token = 'S1i/Zyzd3tBT8awkqjrHBp/AcW1G17eS7nMK55bMDwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}