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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd89c51a69357570c4a79e4c8f1879929644263ef4f8a49b72255d8bbc24b7ea6' 
  AND token = 'ObLwEOKSRbIOavw7pRRg2YX3vUSV96a7IPf/3+Lf8xw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}