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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3b7f1e78ec1c1e6843d374f2be81e247d8505563a3e2000e74ff93de61b36cd' 
  AND token = 'IprXbY4q8Lt4zOoqNSViNsK+QmWtxp+IqFtud/uL2ig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}