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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e25e80f6a74356ad625e9c0c50612b862a531cabfa37c62f90b9cb0b45bdebe' 
  AND token = 'gHZZTZoaQh8xclTNCxWWRp7AKIRahlW8igYHoG7QIO8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}