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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6755c11fc809713e6af26d0cde22c06975537527240bf49197024ca90214902' 
  AND token = 'EtNKa+OHCxz0Zk9Eo0xoB0PGK04x7b0C6N9Plt4Gt9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}