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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '951ad6249435de42a9d7e4c15e7c8bb98f588fd809b0aa8d93e8a941f66d88a3' 
  AND token = '25oGDAdFt9waAaiBnWYl1li+EyQZCxg6svSZNKu6Bes=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}