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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '381b9b9ae31b4fef91e1d82477167493436e00aa75e0c362253c21f61adbd34a' 
  AND token = '2Cg268R34guWOQ9gcHOVPGS1tUJwL3g9QTe5zcarBBA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}