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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4b7216c9436280c0d1a8074fc138129a97991ca60a7f322000857903b8ce2bc' 
  AND token = 'sP2rs+RIvSc0Mak+owxqRN+fpJfh9QFAIyqsVVuc4DA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}