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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25ef038cd76157d9d56c48b9fa3b9190c0f470f4440791d14cee78abc9289572' 
  AND token = 'UcizoUsD2Aq4Sf5M48BXt+Rek7JJt+yFbW2wlYYrnOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}