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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65b93f835db1de1515e892a57a834ee03d2ab121d9d5cdd165c35d5d5fd942f8' 
  AND token = 'fFryMmNEo6dkZoSOHfqSwQIgmLYXDswaJoO2IAQT6R8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}