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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '446e6ec3e4c6d0d487925e25ab569bdc679a7f478178ee48e107e4759564ca55' 
  AND token = '0TWkHnlOJZsMbHMYVhNJdeWGHCgTJEfAkx6jxjCZ3gg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}