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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd074ff72e64c0f93351f4f284f53681741c305187be5a9fcd8d1997d1835f2aa' 
  AND token = 'Y/2VkaaLnTYgrNw9gnI+zTigA6DDcGdkAWqWglf5OGE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}