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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2228022f805e5ae0bd49f38727e3af43a1c0333eb696d017302a97560128c87f' 
  AND token = 'uLaIaKt7VyROdIkFYBCqm3AoWYBelApkT72hAkSYpio=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}