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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50e5a9e7223cc4ecddedd5219b88c89c15336a77a5bef28f4f006837c4e280b5' 
  AND token = 'F/Gl433i5kc89LMNbS3vK/hQvuXfYIRxw4j1szxPo+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}