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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '734a38314ffac70b94aa0a2f4ac634b7f11a8f2295caf93b1d954b2489a164a4' 
  AND token = 'j77ZXxxJ3PvrBRBzB5XT7gjokENO+NNZY/AxT0MUxwQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}