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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53d3158cc66806649ee709c3e32d29710b444a1d309d18be017bdfbe79693886' 
  AND token = 'WsS98sW31nhlTlspnXWWYFz1+SjQ7qnllImIP0E4ExA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}