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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8103a5ae7aa20f4284574d35f9bf8188216c98d359ad0ba4168eaeb036e77332' 
  AND token = '6od46UDDzya78tkvBRd3K34sbH59foDVTtTBk2nV9Y4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}