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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78d61663e0807a2bbacb82b9add0a7bf9780d22eabea5403cd1d9a101a3937ea' 
  AND token = 'awHW2cFI3IykHjnerir1dAgeLQOMgHF1ai7FqDG+4V4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}