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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '379c3e3a7af97b86edeabf04571bf43524eadbb5a8465f2962a35238379b90ed' 
  AND token = '4Qn3LuktQdjWgbcL32Fh0E3Qr6cAQpmAx+9FG9UM1ow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}