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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af5fefbca0a09f2dbeb2a80b6bd10471e29de178c901f036952d09d91e2a4d5a' 
  AND token = 'Umr+2pNfZqnXzLDIW5N96JGCCycrwuDMFgJOphxNPZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}