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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b375605c708764aee402b3bb361f7b46e654fa1a88eec300b6c69420a07509d' 
  AND token = 'dAEomQZSvBQ7rb5rAVM+9WJaHutbXK8h1LjG+FO1pfo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}