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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '431f521f72b56fd32afeb7d14943c47271d7c317e7984405e4e61197c49dc95a' 
  AND token = '352HtEis4yYaIZ94RLbluFIzBdi2+PXmywn8Pt6Dh0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}