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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb14dc393a6fb5a07ac3557d5581a227d636090a70501e744dcab7ef6f751221' 
  AND token = 'iSarGA0jN+iWYnZ0eIRw6KAAuUzyUV13mJ31XYHF4+o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}