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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '481bb4d41289cee8b3f973f1f78175eed85a4fa8bef65a5200996dd1395c14ab' 
  AND token = 'pPIwmoc+p9SIL8CideiWipH4NoU6M2pKaws+PQPId/w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}