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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15997ea96b1b4cbe15a13139152998b411b9eac4e771e1536bad567bbd198d63' 
  AND token = 'uV/1d3Zkd0mXPiEYUwSy+PgT/deGpfJNznc/6THlfK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}