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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ff3d914a8b511a4d08499f5db4f1da63599e38f7b0b8a959254f8d0781a0619' 
  AND token = 'gGw9dKsOI2yr1+37boJe2dfDLb5QH7D+/ZQepDfAQEw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}