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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9ea893297833b1dbcb1aa48cfcdfbf62d0a3da22555bbb80e481e5349ac25d8' 
  AND token = 'YZ9cT7Tvt1By/gOj4txTis2XXMEwM4a7NaRU0NaTNE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}