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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7801f69c9d57a51211b550665d70df19a83348d2c0261fde9ae9c9cc485016f7' 
  AND token = '+YkPE1p/C5WaGDPy9/bPyJCCDUvP+zOhNVi7jh3ipN4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}