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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f90f6edf64318e1bee4ecb895e3f40b24a9cea0a660cbdfb5ca964a1ea34389' 
  AND token = 'cGvld3LE1rfed56xE/LUQjC6XjuccAV4MApI4OY6gQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}