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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a601754484f73cc110caee24cc11cded4e5ad123574746c25b61ff357156223' 
  AND token = '79XNtFgZNuu+GJAyO8LW5nItiHiVrs84TQcmUXb179Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}