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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4000a728f71418473e8fd78c66f73d5a3c9b1666c22e2a5c53d9c9f7ca1adeec' 
  AND token = 'o2gayP+HJpqtFmXROY/oZnyX1b8fsLLel0LytkRKj+A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}