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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51d760b4363f7d4d95b6ed1088d1ebea2cc139b33fcce1aa1b2ec1c6873ad467' 
  AND token = 'kFynSGEZk9+CHOpT7jqmD6HTwXjL82jZqHmcXYHisTI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}