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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89c50342c52e600f78aebf2fca8a5734466f093e1213365c4918134b4b66f599' 
  AND token = 'zNK+8nQSIxoHEWlOMt38yKrPhU+/pzkX3ntB2WF7vS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}