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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '785f21634dd6c361638ce4596254b1b3598c316a180847462ca147dd173f0b15' 
  AND token = 'TK7Rx94S4tIx02vkbOjNGMV9r5GjySbB7/keYUHmCA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}