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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5c8a3b02a35202f4bffcf14eef5a365aa10d42fbbc8df4d03283f59045c878c' 
  AND token = 'wGL8M3hvRpfW5k5vRLVEtKX9HgZ8OnkdMTEX1mdOCpo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}