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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '201041bfd3a30f7cebe4da81e71ea2916e49e91ceff25ff2d5581f807d4296a4' 
  AND token = 'RIp3ozHAnQLSmKcv7lUvHfWMymy9I/2FjXIfXJU5M/Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}