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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '722531215e34ca9ed56693013f746cc80f3faad46a85949a45d4d37f77b92001' 
  AND token = 'n+H+yH02jR628PdVj3ZgAdHF6pO2ZnT50bf7LnDNO2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}