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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ba44065ba57729a5fd4bfd91bbec4d106bd9df3edda45ab5ad7a78898577c6d' 
  AND token = 'PJpLj3ZQhyDkMIO+dUbvXBFrzM0nK7FT0LdoJ6s2w1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}