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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '460381e545340707409712e3e759bba1f8cd4500fd1630da98471e1770bc1a29' 
  AND token = 'A43KWlPTxAwXnwNi8+5nFXYS4c3a+ZccVLhMnT8ovos=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}