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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8924794c4781bb8479215258922c5796df73b354030d9755add7c1f46e2ad523' 
  AND token = 'mxQ0icjnLQsnCa7XBouUPo9NLBa/CYaiBOGQlXzfruc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}