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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e56f2bb432f6ac1fe0e34d06100e90ecf4b929a3375f80e62efeee5d604e6f2' 
  AND token = 'UJHOt16bMGVHx3NfCB1IMbM2LGu8rYx5lT/V3aQEvfI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}