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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df09329988fa9d2761ab495d14998723815d02d8753f469c7327907ef0351c02' 
  AND token = 'EzIfieNtCN2BJenVY1+k4QGKMlwsAmaahSedROByDuo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}