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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64a5b3ecaaf5067a2f35352b6cdce9e848b3f8281c798b827297fa28ba103ba1' 
  AND token = 'WBc0IAsLTLuutdRdsv0sZqcCVZGfNO2mt+M/Sb9fzkY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}