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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3075f5d4bf642c735e0931744e8237a4cc3d067564c2fb861a2177523600d58' 
  AND token = 'ttBwSUjRCBvs6Fbayyb1lRsCA6Yi2BcN7sZPmx1sa7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}