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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '574a70a4c9b69f6467886a4b252b44d69241842cd8409c8dacb384b050c5d972' 
  AND token = 'J0eiJr9z+wpol05q1u4XcDUKX6beGcEy+PzbKwHWq4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}