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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c2f0095d3268f5e5cb70a6daa888a37f063a827900521770ed9373cb71d4c45' 
  AND token = '+DZvCF1rG/4eluMNWAouKpHXpdNaG3Gi2mHX6tn3Jsc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}