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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7de2220aaad21fef9b1e01c6d150c4baeab3c5042d13f1cb06db8613c4411708' 
  AND token = 'XYrR7u/hd2qAtftzPFGoqXJj8O4zZ0ZAlOOWi5ALU84=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}