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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6c4b50a1f1f764a60656c245ae44775b80d913ddb8d31f705f3b0f883e8bb40' 
  AND token = '5Kqi6bg66hQ+E6kA8S5AFIr1A9WO0+JNUdtpCA9Mqhw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}