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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c43d020155efdfa0eb64e8f468683a7ea65c04ec716fbd046be50f3090a99823' 
  AND token = 'qnubB3DAc3KsrEqY95ZaVu4wq0NEE8QZABW9IEnclr0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}