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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88e74ea36b90d1969eb43b1bdd47e97d6d04ab03627539ca75264c14c1ed34df' 
  AND token = 'l2YokUaryEtWrS3WrSnPRxy4PqiG85bFDCNPZekg5eQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}